TURMERIC/CURCUMIN AND CARDIOVASCULAR DISEASE

    TURMERIC/CURCUMIN AND CARDIOVASCULAR DISEASE
  1. Turmeric is obtained from the root of a plant (Curcuma longa L.). Turmeric has many healthy substances such as thiamine, riboflavin, niacin, ascorbic acid, calcium, phosphorous, sodium and potassium.
  2. Turmeric has also a substance called curcumin, which is what gives most of it’s positive effects in the body and also is what gives to turmeric the yellow color. Curcumin has many protective benefits to the heart [1];
  3. Turmeric has anti inflammatory characteristics that have been tested by science [2,3];
  4. Curcumin may also have antithrombotic (diminishes clot formation) [4,5];
  5. It can improve endothelial function in patients with type 2 diabetes [6];
  6. The only problem using turmeric might be the absorption of curcumin, which is quite small when taking alone. But if turmeric is taken with black peper (which contains a substance called peperine), then the peperine helps to increase the absorption of curcumin [7];
  7. It has antioxidant effects [8]; 
  8. At least two studies realized in rats showed that curcumin might prevent heart failure [9, 10];
  9. Curcumin is notably effective in the protection of the heart after a biopass surgery (CABG - coronary artery bypass grafting), decreasing the incidence of myocardial infarct after heart surgeries [11];
  10. Curcumin is also known for been a potent anti-cancer agent with many mechanisms of action [12, 13];
  11. Turmeric might have effect of improvment endothelial function in postmenopausal women when used associated with aeorobic training exercices [14];  
  12. Additionally, curcumin may also have anti-atherogenic (avoid plaque formation) effect [15];
  13. I suggest you to find sellers online (e.g. Amazon.com) that sell it in a larger quantity portion, which makes it last a lot longer and it is normally less expensive too;
  14. In average I take about one spoon of in two different meals per day (lunch and dinner). I add a bit of black pepper on the top of it to help with the increase of absorption of curcumin. I put it above the food in my plate and mix it up, it’s delicious!
  15. And please go ahead and check out more about supplements to the heart such as vitamin d3 and CoQ10 (coenzime Q10).

Disclaimer: This article is not meant to give any medical advice, diagnosis or treatment. Views existed here do not necessarily match those of Biohacking your Heart! or its staff. The information presented on this article does not intend to surrogate a consult with your health care professional and does not have the intention of giving any medical suggestion. Do not use the information obtained on this website to diagnose, treat, or prescribe any medications or supplements. The information regarding supplementation have not been evaluated by the US Food and Drug Administration and does not have the intention of diagnose, treat or prevent any disease. By using this website you accept all the terms in the disclaimer in full extent. If you don’t agree with any of this disclaimer do not use https://biohackingyourheart.blogspot.com/. We have the right to change this terms any time we judge it's necessary. Therefore you should check out for updates periodically. All information is based on science research and on the life experiencing of the author and by no means should be used as an example to be copy out. You should always consult your health care professional before do anything regarding your health.

Copyright © 2017 Biohacking your Heart. All Rights Reserved.
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REFERENCES

[1] Kapakos G, Youreva V and Srivastava AK. (2012). Cardiovascular protection by curcumin: molecular aspects. Indian J Biochem Biophys. Oct;49(5):306-15.
[2] Chainani-Wu N, Madden E, Lozada-Nur F, Silverman S Jr. (2012). High-dose curcuminoids are efficacious in the reduction in symptoms and signs of oral lichen planus. J Am Acad Dermatol. May;66(5):752-60.
[3] Khajehdehi P, Pakfetrat M, Javidnia K, Azad F, Malekmakan L, Nasab MH and Dehghanzadeh G. (2011).  Oral supplementation of turmeric attenuates proteinuria, transforming growth factor-β and interleukin-8 levels in patients with overt type 2 diabetic nephropathy: a randomized, double-blind and placebo-controlled study. Scand J Urol Nephrol. Nov;45(5):365-70.
[4] Srivastava R, Dikshit M, Srimal RC and Dhawan BN. (1985). Anti-thrombotic effect of curcumin. Thrombosis Research, 40(3):413–417.
[5] Sirisidthi K, Kosai P, Jiraungkoorskul K and Jiraungkoorskul W. (2016). Antithrombotic activity of turmeric (Curcuma longa): A review. Indian J. Agric. Res., 50(2): 101-106.
[6] Usharani P, Mateen AA, Naidu MU, Raju YS, Chandra N. (2008). Effect of NCB-02, atorvastatin and placebo on endothelial function, oxidative stress and inflammatory markers in patients with type 2 diabetes mellitus: a randomized, parallel-group, placebo-controlled, 8-week study. Drugs R D.;9(4):243-50.
[7] Shoba G, Joy D, Joseph T et al. (1998). Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. May;64(4):353-6.
[8] Meng B, Li J and Cao H. (2013). Antioxidant and antiinflammatory activities of curcumin on diabetes mellitus and its complications. Current Pharmaceutical Design 19:2101–2113.
[9] Morimoto T, Sunagawa Y, Kawamura T, Takaya T, Wada H, Nagasawa A, Komeda M, Fujita M, Shimatsu A, Kita T and Hasegawa K. (2008 ). The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats. J Clin Invest. Mar; 118(3):868-78.
[10] Li HL, Liu C, de Couto G, Ouzounian M, Sun M, Wang AB, Huang Y, He CW, Shi Y, Chen X, Nghiem MP, Liu Y, Chen M, Dawood F, Fukuoka M, Maekawa Y, Zhang L, Leask A, Ghosh AK, Kirshenbaum LA and Liu PP. (2008). Curcumin prevents and reverses murine cardiac hypertrophy. J Clin Invest. Mar; 118(3):879-93.
[11] Wongcharoen W, Jai-aue S, Phrommintikul A et al. (2012). Effects of Curcuminoids on Frequency of Acute Myocardial Infarction After Coronary Artery Bypass Grafting. Am J Cardiol. Jul 1;110(1):40-4.
[12] Shanmugam MK, Rane G, Kanchi MM. (2015). The Multifaceted Role of Curcumin in Cancer Prevention and Treatment. Molecules, 20(2):2728-2769.
[13] Anand P, Sundaram C, Jhurani S. (2008). Curcumin and cancer: An “old-age” disease with an “age-old” solution. Cancer Letters. 267(1):133-164.
[14] Akazawa N, Choi Y, Miyaki A, Tanabe Y, Sugawara J, Ajisaka R and Maeda S. (2012). Curcumin ingestion and exercise training improve vascular endothelial function in postmenopausal women. Nutr Res. Oct;32(10):795-9.
[15] Olszanecki R,  Jawień J,  Gajda M,  Mateuszuk L,  Gebska A,  Korabiowska M,  Chłopicki S and  Korbut R.  (2005). Effect of curcumin on atherosclerosis in apoE/LDLR-double knockout mice.  Journal of Physiology and Pharmacology : an Official Journal of the Polish Physiological Society. 01 Dec, 56(4):627-635].

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Copyright © 2017 Biohacking your heart. All Rights Reserved. November 23, 2017.


  



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